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BI-22 CORRELATION OF MOLECULAR SUBTYPES WITH OVERALL SURVIVAL (OS) IN AVAGLIO, A RANDOMIZED, PLACEBO-CONTROLLED STUDY OF BEVACIZUMAB (BEV) PLUS RADIOTHERAPY (RT) AND TEMOZOLOMIDE (TMZ) FOR NEWLY DIAGNOSED GLIOBLASTOMA (GBM)
BACKGROUND: Factors that correlate the extent of clinical benefit with anti-VEGF therapy are poorly understood. Two phase 3 trials in newly diagnosed GBM (AVAglio and RTOG-0825) reported that BEV + RT/TMZ prolonged progression-free survival but not OS, versus placebo + RT/TMZ. Specific GBM patient s...
Tallennettuna:
| Julkaisussa: | Neuro Oncol |
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| Päätekijät: | , , , , , , , , , , , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Oxford University Press
2014
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4217890/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou239.22 |
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