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AT-03 PHASE I TRIAL OF ENZASTAURIN (LY 317615) IN COMBINATION WITH CARBOPLATIN IN ADULTS WITH RECURRENT GLIOMA
BACKGROUND: Enzastaurin is a selective protein kinase-C β inhibitor with antiangiogenic activity. Preclinical studies support its potential efficacy in combination with carboplatin in high-grade glioma. METHODS: The objective of this open-label phase-I study in adults with refractory high-grade glio...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4217808/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou237.3 |
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