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AT-03 PHASE I TRIAL OF ENZASTAURIN (LY 317615) IN COMBINATION WITH CARBOPLATIN IN ADULTS WITH RECURRENT GLIOMA

BACKGROUND: Enzastaurin is a selective protein kinase-C β inhibitor with antiangiogenic activity. Preclinical studies support its potential efficacy in combination with carboplatin in high-grade glioma. METHODS: The objective of this open-label phase-I study in adults with refractory high-grade glio...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Ambady, Prakash, Kreisl, Teri, Warren, Katherine, McNeill, Katherine, Fine, Howard
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Oxford University Press 2014
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4217808/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou237.3
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