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A phase I/II trial of enzastaurin in patients with recurrent high-grade gliomas
Enzastaurin, a potent inhibitor of protein kinase C-beta, inhibits angiogenesis and has direct cytotoxic activity against glioma cells in preclinical studies. Patients with recurrent high-grade gliomas were stratified by histology and use of enzyme-inducing antiepileptic drugs (EIAEDs). Patients on...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2940576/ https://ncbi.nlm.nih.gov/pubmed/20150385 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nop042 |
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