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Using Data Augmentation to Facilitate Conduct of Phase I–II Clinical Trials with Delayed Outcomes
A practical impediment in adaptive clinical trials is that outcomes must be observed soon enough to apply decision rules to choose treatments for new patients. For example, if outcomes take up to six weeks to evaluate and the accrual rate is one patient per week, on average three new patients will b...
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| Pubblicato in: | J Am Stat Assoc |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4217535/ https://ncbi.nlm.nih.gov/pubmed/25382884 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/01621459.2014.881740 |
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