TLR-dependent phagosome tubulation in dendritic cells promotes phagosome cross-talk to optimize MHC-II antigen presentation

Dendritic cells (DCs) phagocytose large particles like bacteria at sites of infection and progressively degrade them within maturing phagosomes. Phagosomes in DCs are also signaling platforms for pattern recognition receptors, such as Toll-like receptors (TLRs), and sites for assembly of cargo-deriv...

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Detaylı Bibliyografya
Asıl Yazarlar: Mantegazza, Adriana R., Zajac, Allison L., Twelvetrees, Alison, Holzbaur, Erika L. F., Amigorena, Sebastián, Marks, Michael S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2014
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4217451/
https://ncbi.nlm.nih.gov/pubmed/25313083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1412998111
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