Synthetic Flavonoids, Aminoisoflavones: Interaction and Reactivity with Metal-Free and Metal-Associated Amyloid-β Species

Metal ion homeostasis in conjunction with amyloid-β (Aβ) aggregation in the brain has been implicated in Alzheimer’s disease (AD) pathogenesis. To uncover the interplay between metal ions and Aβ peptides, synthetic, multifunctional small molecules have been employed to modulate Aβ aggregation in vit...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: DeToma, Alaina S., Krishnamoorthy, Janarthanan, Nam, Younwoo, Lee, Hyuck Jin, Brender, Jeffrey R., Kochi, Akiko, Lee, Dongkuk, Onnis, Valentina, Congiu, Cenzo, Manfredini, Stefano, Vertuani, Silvia, Balboni, Gianfranco, Ramamoorthy, Ayyalusamy, Lim, Mi Hee
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4217218/
https://ncbi.nlm.nih.gov/pubmed/25383163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4sc01531b
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados