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Human MUC1 carcinoma-associated protein confers resistance to genotoxic anticancer agents

The MUC1 transforming protein is overexpressed by most human carcinomas. The present studies demonstrate that the MUC1 C-terminal subunit (MUC1 C-ter) localizes to mitochondria in HCT116/MUC1 colon carcinoma cells and that heregulin stimulates mitochondrial targeting of MUC1 C-ter. We also show that...

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Detalhes bibliográficos
Main Authors: Ren, Jian, Agata, Naoki, Chen, Dongshu, Li, Yongqing, Yu, Wei-hsuan, Huang, Lei, Raina, Deepak, Chen, Wen, Kharbanda, Surender, Kufe, Donald
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4217165/
https://ncbi.nlm.nih.gov/pubmed/14998492
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