Promoting PGC-1α-driven mitochondrial biogenesis is detrimental in pressure-overloaded mouse hearts

Mitochondrial dysfunction in animal models of heart failure is associated with downregulation of the peroxisome proliferator-activated receptor-γ coactivator (PGC)-1α pathway. To test whether PGC-1α is an appropriate therapeutic target for increasing mitochondrial biogenesis and improving function i...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Karamanlidis, Georgios, Garcia-Menendez, Lorena, Kolwicz, Stephen C., Lee, Chi Fung, Tian, Rong
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2014
Materias:
Energetics and Metabolism
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4217009/
https://ncbi.nlm.nih.gov/pubmed/25172896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00280.2014
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares