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Prion Infection of Epithelial Rov Cells Is a Polarized Event

During prion infections, the cellular glycosylphosphatidylinositol-anchored glycoprotein PrP is converted into a conformational isoform. This abnormal conformer is thought to recruit and convert the normal cellular PrP into a likeness of itself and is proposed to be the infectious agent. We investig...

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Autori principali: Paquet, Sophie, Sabuncu, Elifsu, Delaunay, Jean-Louis, Laude, Hubert, Vilette, Didier
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC421691/
https://ncbi.nlm.nih.gov/pubmed/15194791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.13.7148-7152.2004
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