MYCN-dependent Expression of Sulfatase-2 Regulates Neuroblastoma Cell Survival

Heparan sulfate proteoglycans (HSPGs) play a critical role in the interaction of tumor cells and their microenvironment. HSPG activity is dictated by sulfation patterns controlled by sulfotransferases, which add sulfate groups, and sulfatases (Sulfs), which remove 6-O-sulfates. Here we report altere...

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Detalhes bibliográficos
Main Authors: Solari, Valeria, Borriello, Lucia, Turcatel, Gianluca, Shimada, Hiroyuki, Sposto, Richard, Fernandez, G. Esteban, Asgharzadeh, Shahab, Yates, Edwin A., Turnbull, Jeremy E., DeClerck, Yves A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4216758/
https://ncbi.nlm.nih.gov/pubmed/25164011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-2513
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