Human Monoclonal Antibody to Hepatitis C Virus E1 Glycoprotein That Blocks Virus Attachment and Viral Infectivity

Human antibodies elicited in response to hepatitis C virus (HCV) infection are anticipated to react with the native conformation of the viral envelope structure. Isolation of these antibodies as human monoclonal antibodies that block virus binding and entry will be useful in providing potential ther...

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Main Authors: Keck, Zhen-Yong, Sung, Vicky M. H., Perkins, Susan, Rowe, Judy, Paul, Sudhir, Liang, T. Jake, Lai, Michael M. C., Foung, Steven K. H.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2004
Fag:
Pathogenesis and Immunity
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC421663/
https://ncbi.nlm.nih.gov/pubmed/15194801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.13.7257-7263.2004
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