Cooperativity in Virus Neutralization by Human Monoclonal Antibodies to Two Adjacent Regions Located at the Amino Terminus of Hepatitis C Virus E2 Glycoprotein

A challenge for hepatitis C virus (HCV) vaccine development is defining conserved epitopes that induce protective antibodies against this highly diverse virus. An envelope glycoprotein (E2) segment located at amino acids (aa) 412 to 423 contains highly conserved neutralizing epitopes. While polyclon...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Keck, Zhenyong, Wang, Wenyan, Wang, Yong, Lau, Patrick, Carlsen, Thomas H. R., Prentoe, Jannick, Xia, Jinming, Patel, Arvind H., Bukh, Jens, Foung, Steven K. H.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2013
Témata:
Pathogenesis and Immunity
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3536422/
https://ncbi.nlm.nih.gov/pubmed/23097455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01941-12
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky