Human Monoclonal Antibodies That Inhibit Binding of Hepatitis C Virus E2 Protein to CD81 and Recognize Conserved Conformational Epitopes

The intrinsic variability of hepatitis C virus (HCV) envelope proteins E1 and E2 complicates the identification of protective antibodies. In an attempt to identify antibodies to E2 proteins from divergent HCV isolates, we produced HCV E2 recombinant proteins from individuals infected with HCV genoty...

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Detalhes bibliográficos
Main Authors: Hadlock, Kenneth G., Lanford, Robert E., Perkins, Susan, Rowe, Judy, Yang, Qing, Levy, Shoshana, Pileri, Piero, Abrignani, Sergio, Foung, Steven K. H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC110915/
https://ncbi.nlm.nih.gov/pubmed/11044085
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