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Targeted Inhibition of ATR or CHEK1 Reverses Radioresistance in Oral Squamous Cell Carcinoma Cells with Distal Chromosome Arm 11q Loss

Oral squamous cell carcinoma (OSCC), a subset of head and neck squamous cell carcinoma (HNSCC), is the eighth most common cancer in the U.S.. Amplification of chromosomal band 11q13 and its association with poor prognosis has been well established in OSCC. The first step in the breakage-fusion-bridg...

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Библиографические подробности
Главные авторы: Sankunny, Madhav, Parikh, Rahul A., Lewis, Dale W., Gooding, William E., Saunders, William S., Gollin, Susanne M.
Формат: Artigo
Язык:Inglês
Опубликовано: 2013
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4216593/
https://ncbi.nlm.nih.gov/pubmed/24327542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gcc.22125
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