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Targeted Inhibition of ATR or CHEK1 Reverses Radioresistance in Oral Squamous Cell Carcinoma Cells with Distal Chromosome Arm 11q Loss

Oral squamous cell carcinoma (OSCC), a subset of head and neck squamous cell carcinoma (HNSCC), is the eighth most common cancer in the U.S.. Amplification of chromosomal band 11q13 and its association with poor prognosis has been well established in OSCC. The first step in the breakage-fusion-bridg...

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Main Authors: Sankunny, Madhav, Parikh, Rahul A., Lewis, Dale W., Gooding, William E., Saunders, William S., Gollin, Susanne M.
格式: Artigo
語言:Inglês
出版: 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4216593/
https://ncbi.nlm.nih.gov/pubmed/24327542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gcc.22125
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