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Mapping the route from naive pluripotency to lineage specification

In the mouse blastocyst, epiblast cells are newly formed shortly before implantation. They possess a unique developmental plasticity, termed naive pluripotency. For development to proceed, this naive state must be subsumed by multi-lineage differentiation within 72 h following implantation. In vitro...

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Détails bibliographiques
Auteurs principaux: Kalkan, Tüzer, Smith, Austin
Format: Artigo
Langue:Inglês
Publié: The Royal Society 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4216463/
https://ncbi.nlm.nih.gov/pubmed/25349449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2013.0540
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