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Otx2 and Oct4 Drive Early Enhancer Activation during Embryonic Stem Cell Transition from Naive Pluripotency

Embryonic stem cells (ESCs) are unique in that they have the capacity to differentiate into all of the cell types in the body. We know a lot about the complex transcriptional control circuits that maintain the naive pluripotent state under self-renewing conditions but comparatively less about how ce...

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Detalhes bibliográficos
Main Authors: Yang, Shen-Hsi, Kalkan, Tüzer, Morissroe, Claire, Marks, Hendrik, Stunnenberg, Hendrik, Smith, Austin, Sharrocks, Andrew D.
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4074343/
https://ncbi.nlm.nih.gov/pubmed/24931607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.05.037
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