The Polycomb protein, Bmi1, regulates insulin sensitivity

OBJECTIVE: The Polycomb Repressive Complexes (PRC) 1 and 2 function to epigenetically repress target genes. The PRC1 component, Bmi1, plays a crucial role in maintenance of glucose homeostasis and beta cell mass through repression of the Ink4a/Arf locus. Here we have explored the role of Bmi1 in reg...

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Publicat a:Mol Metab
Autors principals: Cannon, Corey E., Titchenell, Paul M., Groff, David N., El Ouaamari, Abdelfattah, Kulkarni, Rohit N., Birnbaum, Morris J., Stoffers, Doris A.
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2014
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4216405/
https://ncbi.nlm.nih.gov/pubmed/25379404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2014.08.002
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