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The Polycomb protein, Bmi1, regulates insulin sensitivity
OBJECTIVE: The Polycomb Repressive Complexes (PRC) 1 and 2 function to epigenetically repress target genes. The PRC1 component, Bmi1, plays a crucial role in maintenance of glucose homeostasis and beta cell mass through repression of the Ink4a/Arf locus. Here we have explored the role of Bmi1 in reg...
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| Publicado no: | Mol Metab |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4216405/ https://ncbi.nlm.nih.gov/pubmed/25379404 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2014.08.002 |
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