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Suppression and promotion of tumor growth by monoclonal antibodies to ErbB-2 differentially correlate with cellular uptake.

Amplification and overexpression of the erbB-2/neu protooncogene are frequently associated with aggressive clinical course of certain human adenocarcinomas, and therefore the encoded surface glycoprotein is considered a candidate target for immunotherapy. We previously generated a series of anti-Erb...

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Détails bibliographiques
Auteurs principaux: Hurwitz, E, Stancovski, I, Sela, M, Yarden, Y
Format: Artigo
Langue:Inglês
Publié: 1995
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC42164/
https://ncbi.nlm.nih.gov/pubmed/7724565
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