A carregar...
Pen-2 Is Essential for γ-Secretase Complex Stability and Trafficking but Partially Dispensable for Endoproteolysis
[Image: see text] The 19-transmembrane γ-secretase complex generates the amyloid β-peptide of Alzheimer’s disease by intramembrane proteolysis of the β-amyloid precursor protein. This complex is comprised of presenilin, Aph1, nicastrin, and Pen-2. The exact function and mechanism of the highly conse...
Na minha lista:
| Main Authors: | , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American
Chemical Society
2014
|
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4216188/ https://ncbi.nlm.nih.gov/pubmed/24941111 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi500489j |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|