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Characterization of Mycobacterium smegmatis Expressing the Mycobacterium tuberculosis Fatty Acid Synthase I (fas1) Gene

Unlike most other bacteria, mycobacteria make fatty acids with the multidomain enzyme eukaryote-like fatty acid synthase I (FASI). Previous studies have demonstrated that the tuberculosis drug pyrazinamide and 5-chloro-pyrazinamide target FASI activity. Biochemical studies have revealed that in addi...

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Udgivet i:J Bacteriol
Principais autores: Zimhony, Oren, Vilchèze, Catherine, Jacobs, William R.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2004
Fag:
Physiology and Metabolism
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC421601/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15205406/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JB.186.13.4051-4055.2004
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