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Characterization of Mycobacterium smegmatis Expressing the Mycobacterium tuberculosis Fatty Acid Synthase I (fas1) Gene

Unlike most other bacteria, mycobacteria make fatty acids with the multidomain enzyme eukaryote-like fatty acid synthase I (FASI). Previous studies have demonstrated that the tuberculosis drug pyrazinamide and 5-chloro-pyrazinamide target FASI activity. Biochemical studies have revealed that in addi...

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Detalles Bibliográficos
Main Authors: Zimhony, Oren, Vilchèze, Catherine, Jacobs, William R.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2004
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC421601/
https://ncbi.nlm.nih.gov/pubmed/15205406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.186.13.4051-4055.2004
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