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Characterization of Mycobacterium smegmatis Expressing the Mycobacterium tuberculosis Fatty Acid Synthase I (fas1) Gene
Unlike most other bacteria, mycobacteria make fatty acids with the multidomain enzyme eukaryote-like fatty acid synthase I (FASI). Previous studies have demonstrated that the tuberculosis drug pyrazinamide and 5-chloro-pyrazinamide target FASI activity. Biochemical studies have revealed that in addi...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2004
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC421601/ https://ncbi.nlm.nih.gov/pubmed/15205406 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.186.13.4051-4055.2004 |
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