Characterization of Mycobacterium smegmatis Expressing the Mycobacterium tuberculosis Fatty Acid Synthase I (fas1) Gene

Unlike most other bacteria, mycobacteria make fatty acids with the multidomain enzyme eukaryote-like fatty acid synthase I (FASI). Previous studies have demonstrated that the tuberculosis drug pyrazinamide and 5-chloro-pyrazinamide target FASI activity. Biochemical studies have revealed that in addi...

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Bibliographic Details

Published in:	J Bacteriol
Main Authors:	Zimhony, Oren, Vilchèze, Catherine, Jacobs, William R.
Format:	Artigo
Language:	Inglês
Published:	American Society for Microbiology (ASM) 2004
Subjects:	Physiology and Metabolism
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC421601/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15205406/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JB.186.13.4051-4055.2004
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