Mitochondrial fusion but not fission regulates larval growth and synaptic development through steroid hormone production

Mitochondrial fusion and fission affect the distribution and quality control of mitochondria. We show that Marf (Mitochondrial associated regulatory factor), is required for mitochondrial fusion and transport in long axons. Moreover, loss of Marf leads to a severe depletion of mitochondria in neurom...

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Détails bibliographiques
Auteurs principaux: Sandoval, Hector, Yao, Chi-Kuang, Chen, Kuchuan, Jaiswal, Manish, Donti, Taraka, Lin, Yong Qi, Bayat, Vafa, Xiong, Bo, Zhang, Ke, David, Gabriela, Charng, Wu-Lin, Yamamoto, Shinya, Duraine, Lita, Graham, Brett H, Bellen, Hugo J
Format: Artigo
Langue:Inglês
Publié: eLife Sciences Publications, Ltd 2014
Sujets:
Developmental Biology and Stem Cells
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4215535/
https://ncbi.nlm.nih.gov/pubmed/25313867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.03558
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