Mitochondrial fusion but not fission regulates larval growth and synaptic development through steroid hormone production

Mitochondrial fusion and fission affect the distribution and quality control of mitochondria. We show that Marf (Mitochondrial associated regulatory factor), is required for mitochondrial fusion and transport in long axons. Moreover, loss of Marf leads to a severe depletion of mitochondria in neurom...

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Detalhes bibliográficos
Main Authors: Sandoval, Hector, Yao, Chi-Kuang, Chen, Kuchuan, Jaiswal, Manish, Donti, Taraka, Lin, Yong Qi, Bayat, Vafa, Xiong, Bo, Zhang, Ke, David, Gabriela, Charng, Wu-Lin, Yamamoto, Shinya, Duraine, Lita, Graham, Brett H, Bellen, Hugo J
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2014
Assuntos:
Developmental Biology and Stem Cells
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4215535/
https://ncbi.nlm.nih.gov/pubmed/25313867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.03558
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