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Cerebellar pathology in Friedreich's ataxia: Atrophied dentate nuclei with normal iron content

BACKGROUND: In Friedreich's ataxia (FA) the genetically decreased expression of the mitochondrial protein frataxin leads to disturbance of the mitochondrial iron metabolism. Within the cerebellum the dentate nuclei (DN) are primarily affected. Histopathological studies show atrophy and accumula...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Solbach, K., Kraff, O., Minnerop, M., Beck, A., Schöls, L., Gizewski, E.R., Ladd, M.E., Timmann, D.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Elsevier 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4215469/
https://ncbi.nlm.nih.gov/pubmed/25379420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nicl.2014.08.018
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