Friedreich's Ataxia Causes Redistribution of Iron, Copper, and Zinc in the Dentate Nucleus

Friedreich's ataxia (FRDA) causes selective atrophy of the large neurons of the dentate nucleus (DN). High iron (Fe) concentration and failure to clear the metal from the affected brain tissue are potential risk factors in the progression of the lesion. The DN also contains relatively high amou...

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Detalhes bibliográficos
Main Authors: Koeppen, Arnulf H., Ramirez, R. Liane, Yu, Devin, Collins, Sarah E., Qian, Jiang, Parsons, Patrick J., Yang, Karl X., Chen, Zewu, Mazurkiewicz, Joseph E., Feustel, Paul J.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2012
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3497958/
https://ncbi.nlm.nih.gov/pubmed/22562713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12311-012-0383-5
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