Next-generation sequencing of adrenocortical carcinoma reveals new routes to targeted therapies

AIMS: Adrenocortical carcinoma (ACC) carries a poor prognosis and current systemic cytotoxic therapies result in only modest improvement in overall survival. In this retrospective study, we performed a comprehensive genomic profiling of 29 consecutive ACC samples to identify potential targets of the...

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Hauptverfasser: Ross, J S, Wang, K, Rand, J V, Gay, L, Presta, M J, Sheehan, C E, Ali, S M, Elvin, J A, Labrecque, E, Hiemstra, C, Buell, J, Otto, G A, Yelensky, R, Lipson, D, Morosini, D, Chmielecki, J, Miller, V A, Stephens, P J
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMJ Publishing Group 2014
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4215283/
https://ncbi.nlm.nih.gov/pubmed/25078331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jclinpath-2014-202514
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