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Critical Role for Lysine 685 in Gene Expression Mediated by Transcription Factor Unphosphorylated STAT3
STAT3 is a pleiotropic transcription factor that is activated by the phosphorylation of tyrosine 705 in response to many cytokines and growth factors. STAT3 without Tyr-705 phosphorylation (U-STAT3) is also a potent transcription factor, and its concentration in cells increases greatly in response t...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4215253/ https://ncbi.nlm.nih.gov/pubmed/25217633 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.603894 |
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