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A matter of access: Nucleosome disassembly from gene promoters is the central goal of transcriptional activators

The mechanism whereby transcriptional activators facilitate transcription activation has been debated. Our recent genome-wide profiling of gene expression during aging, where nucleosomes are depleted, indicates that the function of seemingly all transcriptional activators is to trigger nucleosome di...

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Detalhes bibliográficos
Main Authors: Hu, Zheng, Chen, Kaifu, Li, Wei, Tyler, Jessica K
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4215176/
https://ncbi.nlm.nih.gov/pubmed/25764221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/trns.29355
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