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Epigenetic inheritance of an inducibly nucleosome-depleted promoter and its associated transcriptional state in the apparent absence of transcriptional activators

BACKGROUND: Dynamic changes to the chromatin structure play a critical role in transcriptional regulation. This is exemplified by the Spt6-mediated histone deposition on to histone-depleted promoters that results in displacement of the general transcriptional machinery during transcriptional repress...

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Autori principali: Ohsawa, Ryosuke, Adkins, Melissa, Tyler, Jessica K
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2749832/
https://ncbi.nlm.nih.gov/pubmed/19747370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-8935-2-11
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