B2 Cells Suppress Experimental Abdominal Aortic Aneurysms

Recent reports of rupture in patients with abdominal aortic aneurysm (AAA) receiving B-cell depletion therapy highlight the importance of understanding the role of B cells (B1 and B2 subsets) in the development of AAA. We hypothesized that B2 cells aggravate experimental aneurysm formation. The IHC...

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Main Authors: Meher, Akshaya K., Johnston, William F., Lu, Guanyi, Pope, Nicolas H., Bhamidipati, Castigliano M., Harmon, Daniel B., Su, Gang, Zhao, Yunge, McNamara, Coleen A., Upchurch, Gilbert R., Ailawadi, Gorav
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Investigative Pathology 2014
Assuntos:
Regular Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4215033/
https://ncbi.nlm.nih.gov/pubmed/25194661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2014.07.006
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