Prostate Cancer Characteristics Associated with Response to Pre-Receptor Targeting of the Androgen Axis

BACKGROUND: Factors influencing differential responses of prostate tumors to androgen receptor (AR) axis-directed therapeutics are poorly understood, and predictors of treatment efficacy are needed. We hypothesized that the efficacy of inhibiting DHT ligand synthesis would associate with intra-tumor...

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Hauptverfasser: Mostaghel, Elahe A., Morgan, Andrew, Zhang, Xiaotun, Marck, Brett T., Xia, Jing, Hunter-Merrill, Rachel, Gulati, Roman, Plymate, Stephen, Vessella, Robert L., Corey, Eva, Higano, Celestia S., Matsumoto, Alvin M., Montgomery, R. Bruce, Nelson, Peter S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4214744/
https://ncbi.nlm.nih.gov/pubmed/25356728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0111545
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