Genome-Wide Association Identifies Regulatory Loci Associated with Distinct Local Histogram Emphysema Patterns

Rationale: Emphysema is a heritable trait that occurs in smokers with and without chronic obstructive pulmonary disease. Emphysema occurs in distinct pathologic patterns, but the genetic determinants of these patterns are unknown. Objectives: To identify genetic loci associated with distinct pattern...

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Detalhes bibliográficos
Main Authors: Castaldi, Peter J., Cho, Michael H., San José Estépar, Raúl, McDonald, Merry-Lynn N., Laird, Nan, Beaty, Terri H., Washko, George, Crapo, James D., Silverman, Edwin K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4214129/
https://ncbi.nlm.nih.gov/pubmed/25006744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201403-0569OC
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