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Assessing pleiotropy and mediation in genetic loci associated with chronic obstructive pulmonary disease

Genetic association studies have increasingly recognized variant effects on multiple phenotypes. Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease with environmental and genetic causes. Multiple genetic variants have been associated with COPD, many of which show significant ass...

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Detalhes bibliográficos
Publicado no:Genet Epidemiol
Main Authors: Parker, Margaret M., Lutz, Sharon M., Hobbs, Brian D., Busch, Robert, McDonald, MerryLynn N., Castaldi, Peter J., Beaty, Terri H., Hokanson, John E., Silverman, Edwin K., Cho, Michael H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6416067/
https://ncbi.nlm.nih.gov/pubmed/30740764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.22192
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