C/EBPα and MYB regulate FLT3 expression in AML

The interaction between the receptor FLT3 (FMS-like tyrosine kinase-3) and its ligand FL leads to crucial signalling during the early stages of the commitment of haematopoietic stem cells. Mutation or over-expression of the FLT3 gene, leading to constitutive signalling, enhances the survival and exp...

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Bibliografiske detaljer
Main Authors: Volpe, G, Walton, DS, Del Pozzo, W, Garcia, P, Dassé, E, O’Neill, LP, Griffiths, M, Frampton, J, Dumon, S
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4214120/
https://ncbi.nlm.nih.gov/pubmed/23340802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2013.23
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