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C/EBPα and MYB regulate FLT3 expression in AML
The interaction between the receptor FLT3 (FMS-like tyrosine kinase-3) and its ligand FL leads to crucial signalling during the early stages of the commitment of haematopoietic stem cells. Mutation or over-expression of the FLT3 gene, leading to constitutive signalling, enhances the survival and exp...
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| 主要な著者: | , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4214120/ https://ncbi.nlm.nih.gov/pubmed/23340802 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2013.23 |
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