Distinct regulation of c-myb gene expression by HoxA9, Meis1 and Pbx proteins in normal hematopoietic progenitors and transformed myeloid cells

The proto-oncogenic protein c-Myb is an essential regulator of hematopoiesis and is frequently deregulated in hematological diseases such as lymphoma and leukemia. To gain insight into the mechanisms underlying the aberrant expression of c-Myb in myeloid leukemia, we analyzed and compared c-myb gene...

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Autores principales: Dassé, E, Volpe, G, Walton, D S, Wilson, N, Del Pozzo, W, O'Neill, L P, Slany, R K, Frampton, J, Dumon, S
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2012
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3389162/
https://ncbi.nlm.nih.gov/pubmed/22829978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bcj.2012.20
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