Characterization of Pseudomonas aeruginosa LpxT reveals dual positional lipid A kinase activity and coordinated control of outer membrane modification

Gram-negative bacteria have evolved modification machinery to promote a dynamic outer membrane in response to a continually fluctuating environment. The kinase LpxT, for example, adds a phosphate group to the lipid A moiety of some Gram-negatives including Escherichia coli and Salmonella enterica. L...

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Main Authors: Nowicki, Emily M., O’Brien, John P., Brodbelt, Jennifer S., Trent, M. Stephen
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4213358/
https://ncbi.nlm.nih.gov/pubmed/25223756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.12796
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