The Multidrug Resistance 1 Gene Abcb1 in Brain and Placenta: Comparative Analysis in Human and Guinea Pig

The Multidrug Resistance 1 (MDR1; alternatively ABCB1) gene product P-glycoprotein (P-gp), an ATP binding cassette transporter, extrudes multiple endogenous and exogenous substrates from the cell, playing an important role in normal physiology and xenobiotic distribution and bioavailability. To date...

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Main Authors: Pappas, Jane J., Petropoulos, Sophie, Suderman, Matthew, Iqbal, Majid, Moisiadis, Vasilis, Turecki, Gustavo, Matthews, Stephen G., Szyf, Moshe
格式: Artigo
語言:Inglês
出版: Public Library of Science 2014
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4213008/
https://ncbi.nlm.nih.gov/pubmed/25353162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0111135
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