P‐Glycoprotein (P‐gp)/ABCB1 plays a functional role in extravillous trophoblast (EVT) invasion and is decreased in the pre‐eclamptic placenta

Dysregulation of trophoblast differentiation is implicated in the placental pathologies of intrauterine growth restriction and pre‐eclampsia. P‐glycoprotein (P‐gp encoded by ABCB1) is an ATP‐binding cassette transporter present in the syncytiotrophoblast layer of the placenta where it acts as a mole...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Dunk, Caroline E., Pappas, Jane J., Lye, Phetcharawan, Kibschull, Mark, Javam, Mohsen, Bloise, Enrrico, Lye, Stephen J., Szyf, Moshe, Matthews, Stephen G.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6201374/
https://ncbi.nlm.nih.gov/pubmed/30256530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13810
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