Leiomyoma Cells in 3-Dimensional Cultures Demonstrate an Attenuated Response to Fasudil, a Rho-Kinase Inhibitor, When Compared to 2-Dimensional Cultures

Uterine leiomyomata are common benign tumors in women of reproductive age and demonstrate an attenuated response to mechanical signaling that involves Rho and integrins. To further characterize the impairment in Rho signaling, we studied the effect of Rho-kinase inhibitor, fasudil, on extracellular...

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Detaylı Bibliyografya
Asıl Yazarlar: Malik, Minnie, Britten, Joy, Segars, James, Catherino, William H.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: SAGE Publications 2014
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Original Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4212347/
https://ncbi.nlm.nih.gov/pubmed/25084783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1933719114545240
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