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Liarozole inhibits transforming growth factor-β3–mediated extracellular matrix formation in human three-dimensional leiomyoma cultures

OBJECTIVE: To investigate the impact of liarozole on transforming growth factor-β3 (TGF-β3) expression, TGF-β3 controlled profibrotic cytokines, and extracellular matrix formation in a three-dimensional (3D) leiomyoma model system. DESIGN: Molecular and immunohistochemical analysis in a cell line ev...

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Detalhes bibliográficos
Main Authors: Levy, Gary, Malik, Minnie, Britten, Joy, Gilden, Melissa, Segars, James, Catherino, William H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4152900/
https://ncbi.nlm.nih.gov/pubmed/24825427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fertnstert.2014.03.042
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