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Bruton’s tyrosine kinase inhibitors and their clinical potential in the treatment of B-cell malignancies: focus on ibrutinib

Aberrant signaling of the B-cell receptor pathway has been linked to the development and maintenance of B-cell malignancies. Bruton’s tyrosine kinase (BTK), a protein early in this pathway, has emerged as a new therapeutic target in a variety of such malignancies. Ibrutinib, the most clinically adva...

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Bibliografiska uppgifter
Huvudupphovsmän: Aalipour, Amin, Advani, Ranjana H.
Materialtyp: Artigo
Språk:Inglês
Publicerad: SAGE Publications 2014
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4212313/
https://ncbi.nlm.nih.gov/pubmed/25360238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2040620714539906
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