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Bruton tyrosine kinase inhibitors: a promising novel targeted treatment for B cell lymphomas

Constitutive or aberrant signalling of the B cell receptor signalling cascade has been implicated in the propagation and maintenance of a variety of B cell malignancies. Small molecule inhibitors of Bruton tyrosine kinase (BTK), a protein early in this cascade and specifically expressed in B cells,...

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Bibliografische gegevens
Gepubliceerd in:Br J Haematol
Hoofdauteurs: Aalipour, Amin, Advani, Ranjana H.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4444436/
https://ncbi.nlm.nih.gov/pubmed/24111579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bjh.12573
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