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Loss of Tau results in defects in photoreceptor development and progressive neuronal degeneration in Drosophila

Accumulations of Tau, a microtubule-associated protein, into neurofibrillary tangles is a hallmark of Alzheimer’s disease and other tauopathies. However, the mechanisms leading to this pathology are still unclear: the aggregates themselves could be toxic or the sequestration of Tau into tangles migh...

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Detalhes bibliográficos
Main Authors: Bolkan, Bonnie J., Kretzschmar, Doris
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4212004/
https://ncbi.nlm.nih.gov/pubmed/24909306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dneu.22199
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