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Loss of Tau results in defects in photoreceptor development and progressive neuronal degeneration in Drosophila
Accumulations of Tau, a microtubule-associated protein, into neurofibrillary tangles is a hallmark of Alzheimer’s disease and other tauopathies. However, the mechanisms leading to this pathology are still unclear: the aggregates themselves could be toxic or the sequestration of Tau into tangles migh...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4212004/ https://ncbi.nlm.nih.gov/pubmed/24909306 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dneu.22199 |
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