Chronic intermittent ethanol exposure and withdrawal alters (3α,5α)-3-hydroxy-pregnan-20-one immunostaining in cortical and limbic brain regions of C57BL/6J mice

BACKGROUND: The GABAergic neuroactive steroid (3α,5α)-3-hydroxy-pregnan-20-one (3α,5α-THP, allopregnanolone) has been studied during withdrawal from ethanol in humans, rats and mice. Serum 3α,5α-THP levels decreased and brain levels were not altered following acute ethanol administration (2 g/kg) in...

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Hlavní autoři: Maldonado-Devincci, Antoniette M., Cook, Jason B., O'Buckley, Todd K., Morrow, Danielle H., McKinley, Raechel E., Lopez, Marcelo F., Becker, Howard C., Morrow, A. Leslie
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4211975/
https://ncbi.nlm.nih.gov/pubmed/25293837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acer.12530
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