Ongoing Activation of Autoantigen-Specific B cells in Primary Biliary Cirrhosis

The serologic hallmark of primary biliary cirrhosis (PBC), the antimitochondrial response to the E2 component of the pyruvate dehydrogenase complex (PDC-E2), has unique features, including continuous high titers of IgM and IgG reactivity throughout all stages of disease, capable not only of target e...

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Hauptverfasser: Zhang, Jun, Zhang, Weici, Leung, Patrick S.C., Bowlus, Christopher L., Dhaliwal, Sandeep, Coppel, Ross L., Ansari, Aftab A., Yang, Guo-Xiang, Wang, Jinjun, Kenny, Thomas P., He, Xiao-Song, Mackay, Ian R., Gershwin, M. Eric
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4211937/
https://ncbi.nlm.nih.gov/pubmed/25043065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.27313
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