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Apotopes and the Biliary Specificity of Primary Biliary Cirrhosis
Primary biliary cirrhosis (PBC) is characterized by antimitochondrial antibodies (AMA), directed to the E2 component of the pyruvate dehydrogenase complex (PDC-E2). Notwithstanding the presence of mitochondria in virtually all nucleated cells, the destruction in PBC is limited to small intrahepatic...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2665925/ https://ncbi.nlm.nih.gov/pubmed/19185000 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.22736 |
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